James H Morrissey Selected Research

Polyphosphates

1/2022	Influence of Steric Shield on Biocompatibility and Antithrombotic Activity of Dendritic Polyphosphate Inhibitor.
12/2020	Bacterial polyphosphates interfere with the innate host defense to infection.
11/2020	Platelet polyphosphate induces fibroblast chemotaxis and myofibroblast differentiation.
1/2020	Biotechnological synthesis of water-soluble food-grade polyphosphate with Saccharomyces cerevisiae.
12/2019	Polyphosphate, Zn2+ and high molecular weight kininogen modulate individual reactions of the contact pathway of blood clotting.
1/2019	Polyphosphate in thrombosis, hemostasis, and inflammation.
12/2018	Inorganic polyphosphate interacts with nucleolar and glycosomal proteins in trypanosomatids.
10/2018	DNA ladders can be used to size polyphosphate resolved by polyacrylamide gel electrophoresis.
1/2018	Ability of Polyphosphate and Nucleic Acids to Trigger Blood Clotting: Some Observations and Caveats.
1/2018	Design of Polyphosphate Inhibitors: A Molecular Dynamics Investigation on Polyethylene Glycol-Linked Cationic Binding Groups.

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James H Morrissey Research Topics

Disease

24	Thrombosis (Thrombus) 07/2021 - 02/2004
21	Polyps 01/2022 - 10/2007
14	Hemorrhage 01/2022 - 12/2011
12	Inflammation (Inflammations) 11/2020 - 01/2002
5	Sepsis (Septicemia) 12/2020 - 02/2004
3	Vascular System Injuries 02/2006 - 02/2004
2	Wounds and Injuries (Trauma) 01/2022 - 11/2020
2	Thromboinflammation 07/2021 - 01/2021
2	Infections 12/2020 - 01/2009
2	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 11/2020 - 09/2020
2	COVID-19 11/2020 - 09/2020
2	Thrombophilia 11/2020 - 09/2020
2	Venous Thrombosis (Deep-Vein Thrombosis) 11/2020 - 09/2020
2	Plague (Bubonic Plague) 10/2009 - 01/2009
2	Disseminated Intravascular Coagulation 01/2009 - 02/2004
2	Neoplasms (Cancer) 02/2006 - 02/2004
1	Brain Injuries (Brain Injury) 12/2021
1	Hemophilia A (Haemophilia) 01/2018
1	Lung Injury 01/2017
1	Thromboembolism 11/2016
1	Thrombocytopenia (Thrombopenia) 11/2016

Drug/Important Bio-Agent (IBA)

32	PolyphosphatesIBA 01/2022 - 10/2007
15	PolymersIBA 01/2020 - 10/2007
8	FibrinIBA 11/2020 - 01/2009
7	Thrombin FDA Link 12/2021 - 02/2006
7	Phosphates (Orthophosphate)IBA 01/2020 - 12/2009
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2004
6	Heparin (Liquaemin)FDA LinkGeneric 01/2022 - 10/2014
5	Thromboplastin (Tissue Factor)IBA 01/2017 - 02/2004
5	Peptide Hydrolases (Proteases)FDA Link 01/2016 - 01/2009
4	Phospholipids (Phosphatides)FDA LinkGeneric 01/2022 - 01/2018
4	Carrier Proteins (Binding Protein)IBA 11/2020 - 02/2006
4	AnticoagulantsIBA 10/2019 - 10/2014
4	Complement System Proteins (Complement)IBA 01/2019 - 09/2014
4	Nucleic AcidsIBA 10/2018 - 10/2007
4	Factor XI (Plasma Thromboplastin Antecedent)IBA 03/2014 - 12/2009
3	PhosphatidylserinesIBA 01/2022 - 02/2006
3	Histones (Histone)IBA 07/2021 - 08/2011
3	AntibodiesIBA 11/2020 - 09/2015
3	CalciumIBA 12/2018 - 11/2014
3	Blood Coagulation Factors (Coagulation Factor)IBA 01/2018 - 01/2016
3	Factor XIIa (Coagulation Factor XIIa)IBA 01/2017 - 12/2011
3	Factor XII (Hageman Factor)IBA 01/2016 - 12/2009
3	Factor VIIa (Activated Factor VII)IBA 08/2012 - 02/2004
2	PolyethyleneimineIBA 01/2022 - 11/2014
2	Dendrimers (Dendrons)IBA 01/2022 - 11/2014
2	UHRA-10IBA 01/2022 - 11/2014
2	Biomarkers (Surrogate Marker)IBA 12/2021 - 01/2018
2	defibrotideIBA 07/2021 - 01/2021
2	AutoantibodiesIBA 11/2020 - 09/2020
2	Immunoglobulin G (IgG)IBA 11/2020 - 09/2020
2	Prothrombin (Factor II)IBA 09/2020 - 01/2017
2	polyacrylamideIBA 01/2020 - 10/2018
2	EnzymesIBA 01/2020 - 01/2016
2	BradykininIBA 01/2019 - 12/2009
2	GelsIBA 10/2018 - 10/2007
2	DNA (Deoxyribonucleic Acid)IBA 10/2018 - 01/2018
2	RNA (Ribonucleic Acid)IBA 01/2018 - 01/2017
2	AminesIBA 01/2018 - 11/2014
2	Factor XIa (Coagulation Factor XIa)IBA 01/2017 - 09/2015
2	Plasma KallikreinIBA 01/2017 - 12/2009
2	Serine Proteases (Serine Protease)IBA 01/2016 - 02/2004
2	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 12/2012 - 04/2012
2	Hemostatics (Antihemorrhagics)IBA 04/2012 - 01/2009
2	omptin outer membrane protease (omptin)IBA 10/2009 - 01/2009
2	LipopolysaccharidesIBA 10/2009 - 06/2007
2	PlasminogenIBA 10/2009 - 01/2009
2	lipoprotein-associated coagulation inhibitor (TFPI)IBA 10/2009 - 01/2009
1	polyglycerolIBA 01/2022
1	phosphatidylethanolamineIBA 01/2022
1	polycationsIBA 01/2022
1	Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)IBA 12/2021
1	exopolyphosphataseIBA 12/2020
1	Glycoproteins (Glycoprotein)IBA 09/2020
1	Immunoglobulin M (IgM)IBA 09/2020
1	Antiphospholipid AntibodiesIBA 09/2020
1	Immunoglobulin A (IgA)IBA 09/2020
1	Food Additives (Food Additive)IBA 01/2020
1	Ethanol (Ethyl Alcohol)IBA 01/2020
1	PowdersIBA 01/2020
1	Escherichia coli Ppx proteinIBA 12/2018
1	Coloring Agents (Dyes)IBA 10/2018
1	CollagenIBA 01/2018
1	Fibrinogen (Factor I)FDA Link 01/2018
1	P-SelectinIBA 01/2018
1	Hydroxyeicosatetraenoic Acids (HETE)IBA 01/2018
1	LigandsIBA 01/2018
1	AcidsIBA 01/2018
1	Factor VIII (Coagulation Factor VIII)IBA 01/2018
1	Calcium Gluconate (CBG)IBA 01/2018
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 01/2018
1	SolutionsIBA 10/2017
1	Dihydrotachysterol (AT 10)IBA 10/2017
1	Protamines (Protamine Sulfate)FDA Link 01/2017
1	Ellagic AcidIBA 01/2017
1	High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)IBA 01/2017
1	Antigen-Antibody Complex (Immune Complex)IBA 11/2016
1	Platelet Factor 4IBA 11/2016
1	CystamineIBA 01/2016

Therapy/Procedure

3	Therapeutics 01/2017 - 03/2014